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ALFUSIN-D (ALFUZOSIN/DUTASTERIDE) TABLETS: DOSAGE AND ADMINISTRATION
Film-coated oral tablet
The recommended dosage of Alfusin-D is one tablet daily, to be taken immediately after the same meal each day. The tablet should be swallowed whole and should not be chewed or crushed.
Caution should be exercised when alfuzosin is administered in patients with severe renal impairment (creatinine clearance No dose adjustment is necessary for dutasteride in patients with renal impairment.
Alfuzosin is contraindicated for use in patients with moderate or severe hepatic impairment. Although the pharmacokinetics of alfuzosin have not been studied in patients with mild hepatic impairment, caution should be exercised when alfuzosin is administered to such patients.
The effect of hepatic impairment on dutasteride pharmacokinetics has not been studied. Because dutasteride is extensively metabolized, exposure could be higher in hepatically impaired patients.
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Alfusin-D prescribing information
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